Jan 28, 2012 10:58
12 yrs ago
2 viewers *
English term
versus community diagnosis
English to French
Other
Medical: Health Care
A randomized, double-blind study has been conducted in which 87 patients between 8 and 40 years of age who had newly diagnosed type 1 diabetes were assigned to receive infusions of Rituximab or placebo on days 1, 8, 15, and 22 of the study. The primary outcome, assessed 1 year after the first infusion, was the geometric mean area under the curve (AUC) for the serum C-peptide level during the first 2 hours of a mixed-meal tolerance test. Secondary outcomes included safety and changes in the glycated hemoglobin level and insulin dose.At 1 year, the mean AUC for the level of C peptide was significantly higher in the Rituximab group than in the placebo group.A four-dose course of Rituximab partially preserved beta-cell function over a period of 1 year in patients with type 1 diabetes.
Residual beta-cell function results in better glycemic control, less microvascular complications and less hypoglycemia. And consequently, marked clinical benefit might result from preserving the higher levels of C-peptide observed in patients with surveillance versus community diagnosis of type 1 diabetes. In addition C-peptide itself may have biologic effects, most of which are proposed to be beneficial.
Residual beta-cell function results in better glycemic control, less microvascular complications and less hypoglycemia. And consequently, marked clinical benefit might result from preserving the higher levels of C-peptide observed in patients with surveillance versus community diagnosis of type 1 diabetes. In addition C-peptide itself may have biologic effects, most of which are proposed to be beneficial.
Proposed translations
(French)
| 4 | explication |
SJLD
|
| 4 -1 | en comparaison avec le diagnostic de communauté |
transcimed
|
Proposed translations
6 mins
Selected
explication
surveillance diagnosis = concerne des personnes à haut risque de du diabète qui ont été suivi
versus = contre
community diagnosis = diagnostic fait sur présentation des symptômes et manifestations cliniques du diabètes
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895504/
One of the first points to make is that the diagnosis of type 1 diabetes is dramatically different when made in the community, almost always due to presentations with clinical signs and symptoms of marked hyperglycemia, versus when made as part of a surveillance program of high risk non-diabetic subjects.
--------------------------------------------------
Note added at 15 mins (2012-01-28 11:14:12 GMT)
--------------------------------------------------
sorry for the typos!
concerne des personnes à haut risque du diabète qui ont été suivies
manifestations cliniques du diabète
versus = contre
community diagnosis = diagnostic fait sur présentation des symptômes et manifestations cliniques du diabètes
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895504/
One of the first points to make is that the diagnosis of type 1 diabetes is dramatically different when made in the community, almost always due to presentations with clinical signs and symptoms of marked hyperglycemia, versus when made as part of a surveillance program of high risk non-diabetic subjects.
--------------------------------------------------
Note added at 15 mins (2012-01-28 11:14:12 GMT)
--------------------------------------------------
sorry for the typos!
concerne des personnes à haut risque du diabète qui ont été suivies
manifestations cliniques du diabète
4 KudoZ points awarded for this answer.
Comment: "thanks"
-1
1 hr
en comparaison avec le diagnostic de communauté
en conséquence, un bénéfice clinique marqué peut résulter du maintien d'un niveau élévé de C-peptide observé chez les patients sous surveillance en comparaison avec le diagnostic de communauté du diabète de type 1
Pour la notion de "community" , voir la première réfèrence:
Une stratégie qui contribue à la cohésion
horizontale, ce sont par exemple
les “community oriented primary care”4
tels que pratiqués par les maisons
médicales. Cette approche consiste à
formuler, en concertation avec la population
locale, un “community diagnosis”
ou diagnostic de communauté se basant
sur des informations relatives aux
patients et des données statistiques,
à partir duquel on élabore....
voir aussi
--------------------------------------------------
Note added at 3 hrs (2012-01-28 14:36:18 GMT)
--------------------------------------------------
communauté est préfèrable à population car "community" est utilisé ici dans le contexte médical des USA
voir aussi C-peptide in the Natural History of Type 1 Diabetes,
Jerry P. Palmer, MD http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895504/
--------------------------------------------------
Note added at 4 hrs (2012-01-28 15:07:16 GMT)
--------------------------------------------------
The comparison made here is surveillance of C-peptide levels versus community diagnosis
Pour la notion de "community" , voir la première réfèrence:
Une stratégie qui contribue à la cohésion
horizontale, ce sont par exemple
les “community oriented primary care”4
tels que pratiqués par les maisons
médicales. Cette approche consiste à
formuler, en concertation avec la population
locale, un “community diagnosis”
ou diagnostic de communauté se basant
sur des informations relatives aux
patients et des données statistiques,
à partir duquel on élabore....
voir aussi
--------------------------------------------------
Note added at 3 hrs (2012-01-28 14:36:18 GMT)
--------------------------------------------------
communauté est préfèrable à population car "community" est utilisé ici dans le contexte médical des USA
voir aussi C-peptide in the Natural History of Type 1 Diabetes,
Jerry P. Palmer, MD http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895504/
--------------------------------------------------
Note added at 4 hrs (2012-01-28 15:07:16 GMT)
--------------------------------------------------
The comparison made here is surveillance of C-peptide levels versus community diagnosis
Example sentence:
“community diagnosis” ou diagnostic de communauté
Peer comment(s):
| disagree |
Tony M
: No, the comparison is between surveillance (diagnosis) and community diagnosis. Your second ref. quotes the notion of 'population' rather than 'communauté'.
6 mins
|
|
Hi Tony, 1) right, it is diagnosis within the community 2) "diagnostic de communauté" is actually mentionned in my 1st ref. 3) my 2nd ref. is about health research in a community in North Carolina.
|
Discussion